Stem Cells Basic > Cord Blood > Treatable Diseases of Cord Blood

What diseases can be treated by cord blood stem cells (HSCs)?

Successful Transplant Cases of Cord Blood Proved it Significant Medical Value

Up to 113 diseases can be treated by HSCs
Common diseases including cancers, immunity diseases, etc.

Treatable Diseases List

Discover the list of diseases can be treated by cord blood.

Cord Blood FAQs

Any questions? Check most asked questions by the parent.

Diseases Treated with Cord Blood

Cord blood is a rich source of Hematopoietic Stem Cells (HSCs). At present, HSCs have been used to treat up to 113 diseases5,6. These treatable diseases include:

Leukemia (Blood Cancer)
  • Acute Lymphoblastic Leukemia (ALL)
  • Acute Myelogenous Leukemia (AML)
  • Acute Biphenotypic Leukemia
  • Acute Megakaryocytic Leukemia
  • Acute Undifferentiated Leukemia
  • Atypical Chronic Myeloid Leukemia
  • Bilineal Leukemia
  • Biphenotypic Leukemia
  • Chronic Lymphocytic Leukemia (CLL)
  • Chronic Myelogenous Leukemia (CML)
  • Chronic Neutrophilic Leukemia
  • Hemophagocytic Lymphohistiocytosis (HLH)
  • Juvenile Chronic Myelogenous Leukemia (JCML)
  • Juvenile Myelomonocytic Leukemia (JMML)
  • Mixed Phenotype Acute Leukemia
  • Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia
  • Therapy-Related Myelodysplastic Syndromes
Lymphoma
  • Anaplastic Large Cell Lymphoma
  • Blastic Nk Cell Lymphoma
  • Composite Lymphoma
  • Follicular Lymphoma
  • Hodgkin’s Lymphoma
  • Mantle Cell Lymphoma
  • Mycosis Fungoides
  • Non-Hodgkin’s Lymphoma (Burkitt’s Lymphoma)
  • Peripheral T-Cell Lymphoma
Other Disorders of Blood Cell Proliferation
  • Aplastic Anemia
  • Congenital Dyserythropoietic Anemia
  • Dyskeratosis Congenita
  • Fanconi Anemia
  • Paroxysmal Nocturnal Hemoglobinuria (PNH)
  • Beta Thalassemia Major (aka Cooley’s Anemia)
  • Diamond-Blackfan Anemia
  • Pure Red Cell Aplasia
  • Sickle Cell Disease
  • Amegakaryocytosis / Congenital Thrombocytopenia
  • Glanzmann Thrombasthenia
  • Combined Immunodeficiency
  • SCID with Adenosine Deaminase Deficiency (ADA-SCID)
  • X SCID which is X-linked
  • SCID with absence of T & B Cells
  • SCID with absence of T Cells, Normal B Cells
  • Omenn Syndrome
  • Congenital Neutropenia
  • Infantile Genetic Agranulocytosis (Kostmann Syndrome)
  • Myelokathexis
  • Ataxia-Telangiectasia
  • Bare Lymphocyte Syndrome
  • Common Variable Immunodeficiency
  • DiGeorge Syndrome
  • Familial Hemophagocytic Lymphohistiocytosis Type 2
  • Farber Disease
  • Immune Deficiency
  • Hemophagocytic Lymphohistiocytosis
  • Histiocytosis
  • Leukocyte Adhesion Deficiency
  • Lymphoproliferative Disorders
  • Lymphoproliferative Disorder, X-linked (Susceptibility to Epstein-Barr virus)
  • Purine Nucleoside Phosphorylase Deficiency
  • Hyper Igm Syndrome
  • X-Linked Lymphoproliferative Disease
  • X-Linked Chronic Granulomatous Disease
  • Wiskott-Aldrich Syndrome
  • Acute Myelofibrosis
  • Agnogenic Myeloid Metaplasia (Myelofibrosis)
  • Blastic Plasmacytoiddendritic Cell Neoplasm
  • Polycythemia Vera
  • Essential Thrombocythemia
  • Myelodysplastic Syndrome
  • Myeloma Multiplex
  • Chediak-Higashi Syndrome
  • Chronic Granulomatous Disease
  • Neutrophil Actin Deficiency
  • Reticular Dysgenesis
  • Multiple Myeloma
  • Plasma Cell Leukemia
  • Waldenstrom’s Macroglobulinemia
Transplants for Inherited Disorders of the Immune System & Other Organs
  • Cartilage-Hair Hypoplasia
  • Erythropoietic Porphyria
  • Hermansky-Pudlak Syndrome
  • Pearson’s Syndrome
  • Shwachman-Diamond Syndrome
  • Systemic Mastocytosis
Transplants for Inherited Metabolic Disorders
  • Hurler Syndrome (MPS-IH)
  • Scheie Syndrome (MPS-IS)
  • Hunter Syndrome (MPS-II)
  • Sanfilippo Syndrome (MPS-III)
  • Morquio Syndrome (MPS-IV)
  • Maroteaux-Lamy Syndrome (MPS-VI)
  • Sly Syndrome (MPS-VII) (beta-glucuronidase deficiency)
  • Sly Syndrome (MPS-VII) (beta-glucuronidase deficiency)
  • Mucolipidosis II (I-cell Disease)
  • Adrenoleukodystrophy (ALD)
  • Krabbe Disease(Globoid Cell Leukodystrophy)
  • Metachromatic Leukodystrophy
  • Pelizaeus-Merzbacher Disease
  • Niemann-Pick Disease
  • Sandhoff Disease
  • Wolman Disease
  • Saa / Amyloidosis
  • Lesch-Nyhan Syndrome
  • Osteopetrosis
Solid tumors not originating in the blood or immune system
  • Neuroblastoma
  • Medulloblastoma
  • Retinoblastoma
Miscellaneous
  • Erdheim Chester Disease
  • Extracranial Malignant Germ Cell Tumors
  • Nijmegen Breakage Syndrome

Most Asked Questions by Parents Related to Cord Blood Banking

What disease can cord blood heal?

Until June 2016, up to 113 diseases had been treated with cord blood transplants5,6. They could be divided into 7 categories, namely: Leukemia, Lymphomas, other Disorders of Blood Cell Proliferation, Inherited Disorders of Immune System, Inherited Metabolic Disorders, other Cancers and others.

Detail about 113 treatable disease please refer to Diseases Treated by Cord Blood Transplantation.

What is the difference between cord blood and umbilical cord?

Cord blood and umbilical blood contain two different stem cells which are widely adopted in different medical aspects. Cord blood is a rich source of HSCs which can create the blood and immune cells. Cancers, blood-related, immunity and metabolic diseases can be treated by cord blood. Umbilical cord is a rich source of MSCs which can create structural and connective tissues. Apart from minimizing GvHD in directed and unrelated allogeneic cord blood transplants, MSCs can apply to chronic illnesses treatment, regenerative medicines as well as organ and tissue engineering. Since cord blood and umbilical cord are rich sources of different types of stem cells, they may help to repair the body in different ways.

Can the cord blood and umbilical cord be stored permanently?

Stem cells will stop all physiological activities and remain dormant in -196℃ liquid nitrogen. Therefore, the stem cells can be permanently stored theoretically19. Professor Hal E. Broxmeyer (microbiology and immunology) is a pioneer who advocates of cord blood stem cells cryogenic storage. He proved that stem cells stored for years were still very regenerative, indicating that the stem cells stored in 1985 and 1986 could still be applied to patients for transplant33.

On the contrary, there is no factual basis for the claim of stem cells being able to store permanently under -135℃. Noted that using the vapor nitrogen storage system would cause temperature fluctuation upon stem cells storage and thawing and seriously affect the viability of all samples' stem cells.

Almost all public cord blood banks, including worldwide large blood banks, use liquid nitrogen for stem cells storage.

How much does the cord blood storage service charge?

Entrusted by most parents in Hong Kong1, Healthbaby has a very comprehensive service coverage. Apart from the traditional liquid nitrogen storage plan, HealthBaby also pioneered to provide the advanced BioArchive® System. All storage plan of HealthBaby adopts the expensive liquid nitrogen as storage medium to provide the most stable tempertature for stem cell viability, providing the most quality umbilical cord and cord blood storage service.

To cater for different needs of clients, HealthBaby's cord blood and umbilical cord storage plan have very flexible and comprehensive service plan. Regarding cord blood plan, clients could select the storage plan base on the storage and processing system needs.

The umbilical cord and cord blood service fee already includes registration fee, processing fee and 18 years storage fee, no any additional charge during the contracted year. Extra discounted would be provided for registering both umbilical cord and cord blood storage plan. HealthBaby existing customers and other cord blood bank customers could also enjoy special offers. Please contact us for deatils and any enquiries.

For more details of cord blood service plan please refer to Service Plan.

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